GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE

Name	UROTENSIN II (HUMAN)
Synonyms	UROTENSIN II (HUMAN) UROTENSIN II (HUMAN) HYDROCHLORIDE GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE
CAS	251293-28-4

Molecular Formula	C64H85N13O18S2
Molar Mass	1388.57
Appearance	Solid
Storage Condition	-15°C
In vitro study	Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC 50 =0:62±0.17 nM, n=6).
In vivo study	Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction.

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GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE Request for Quotation